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By P. Nicolopoulou-Stamati, M. A. Pitsos (auth.), P. Nicolopoulou-Stamati, L. Hens, C. V. Howard, N. Van Larebeke (eds.)

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1998: I). However, Schmidt (1998) notes that the rate of childhood cancer in the US is increasing by approximately I per cent each year. Notably, cancer is the main cause of death by disease in children between 1 and 14 years of age in the US (ACS, 2002: 10). , 1998: 2223). , 1995). , 1994). , 1996), which in tum makes interpretation difficult and contradictory. Taking into account such limitations, Coleman et al. (1993) report that, since the early 1960s, the 18 A. NOVOGRADEC and S. HARRIS ALI incidence of childhood cancers, particularly childhood leukaemia, has remained relatively stable, or at the very most, has risen moderately in those geographic areas where there are adequate cancer registration systems.

As will be discussed, since the genetic makeup of identical twins is virtually the same, the occurrence of differential cancer rates between twins cannot logically be ascribed to genetic factors, thus pointing to the importance of environmental factors in the onset of cancer. 1. Wildlife Studies Silent Spring by Rachel Carson (1962) was perhaps the first and most influential document that dealt with the issue of how environmental carcinogens, particularly pesticides, may affect a disturbingly large number of different species ranging from robins to caddis fly larvae, to quail, salmon, cats and ultimately humans.

1999) Industrial Ecology: Policy Framework and Implementation, Prentice-Hall, New Jersey. G. (1985) Exposure and response to methyl isocyanate: results of a community based survey in Bhopal, British Journal of Industrial Medicine 45, 469-475. , Jr. 1-1029. W. (1996) Ambient concentrations of pesticides in California, Environmental Science and Technology 30, 1365-1368. Balter, M. (1995) Chernobyl's thyroid cancer toll - research on cancer epidemic caused by Chernobyl nuclear accident, Science 270 (5243), 1758-1759.

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